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Extra resources for Animals in Scientific Research: An Effective Substitute for Man?: Proceedings of a Symposium held in April 1982 under the auspices of the Humane Research Trust

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A. (1977). A method for detecting carcinogenic organic chemicals using mammalian cells in culture. Cancer 36, 558-563. Trosko, J . E. , Yotti, L. P. and Chu, E. H. Y. (1977). Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light induced 6-thioguanine and oubain resistant Chinese hamster cells. Cancer Res . 37 , 188-193 . 45 The design and use of in vitro toxicity tests James W. Bridges, Diane J. Benford and Susan A. K. It is timely to consider critically our present approach to toxicity testing.

Hyman, J. and Leifer, J. (1981). DNA polymerase deficient assay. In Evaluation of Short-Term Tests for Carcinogens, (eds. J. de Serres and J . Ashby). 210-218. Scott , D. (1982). UKEMS Collaborative genotoxicity trial, cytogenetic tests of 4CMB, BC and 4HMB: Summary and appraisal. Mutation Res. 100, 313-331. --Searle, A. G. (1977). The specific locus test in the mouse. In Handbook of Mutagenicity Test Procedures. (ed . J. ) Elsevier Scientific Publishing Co. Amsterdam. 44 Styles, J. A. (1977).

76, 954-957. Bishun, N. , Williams, D. C. and Parke, D. V. (1975) A cytogenic study in women who had used oral contraceptives, and their progeny. , 33, 299-310. , Boyland, E. and Cooling, C. (1967) The respiration of human liver tissue. , 16, 721-724. Brown, D. , Langley, P. , Smith, D. and Taylor D. C. (1974) Metabolism of chloroform I. The metabolism of 14C-chloroform by different species. Xenobiotica, 4, 151-163. Burk, R. F. and Lane, J. M. (1979) Ethane production and liver necrosis in rats after administration of drugs and other chemicals.

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